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Heart Failure Society

American Heart Association

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Research Trials


Ongoing Trials

The consortium is currently enrolling subjects into several heart failure trials including those sponsored by the National Institutes of Health.  If you are interested in volunteering or would simply like information about heart failure trials, contact Shari Mackedanz RN BSN CCRC: Shari.Mackedanz@hcmed.org, 612 347 5195.  

Future Trials

Two Heart Failure trials may begin enrolling soon.   Please check back for more information.

Enrollment Opportunities

If you are interested in volunteering, email Shari Mackedanz to request more information.


Completed Trials

PROMISE - CRT (Prospective Minnesota Study of Echo tissue doppler imaging in Cardiac Resynchronization Therapy). (Enrollment ended 15 December 2006)


EVEREST TRIAL - (Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Long Term Efficacy and Safety of Oral Tolvaptan Tablets in Subjects Hospitalized with Worsening Congestive Heart Failure.

The MHFC is serving as a coordinating center for the EVEREST Trial.


RAPID-CHF (Relief for Acute fluid-overloaded Patients with Decompensated Congestive Heart Failure).

The MHFC has acted as the coordinating center in the following trials. Our role included contract/budget negotiations, site selection, site meeting coordination, site and sponsor communications and site payments.


PEECH trial (Enhanced External Counterpulsation in Heart Failure)


Astellas Inc